Hillar Klandorf

Contact Info Education Working & Teaching Experience
Research Interests Recent Publications

Email - Hillar.Klandorf@mail.wvu.edu
Division of Animal and Veterinary Sciences
College of Agriculture and Forestry
West Virginia University
P.O. Box 6108
Morgantown, WV 26506-6108
Telephone: (304) 293-2631 Ext. 4436
FAX: (304) 293-2232

Education:
· B.S. in Biochemistry, University of California, Los Angeles, CA, 1970-1974
· B.S. in Animal Physiology, University of Arizona, Tucson, AZ, 1974-1976
· Ph.D., British Council for National Academic Awards (CNAA), A.R.C. Poultry Research Center, Roslin, Scotland, 1976-1982

Working and Teaching Experience:
· Professor at West Virginia University, Div. of Animal and Vet. Sci., Morgantown, WV, 2001-Present
· Associate Professor at West Virginia University, Div. of Animal and Vet. Sci., Morgantown, WV, 1994-2001
· Assistant Professor at West Virginia University, Div. of Animal and Vet Sci., Morgantown, WV, 1988-1994
· Adjunct Assistant Professor at UCLA, Dept. of Medicine/Endocrinology, Los Angeles, CA, 1984-1988
· Post-doctoral Research Fellow at Rutgers University, Dept. of Animal Science, New Brunswick, NJ, 1983-1984
· Post-doctoral Research Assistant at University of Hull, Wolfson Institute, S.R.C. Post-doc, Hull, England, 1981-1983

Research Interests:
· Investigating the relationship between oxidative stress and tissue complications in poultry
· Measuring age related changes between the crosslink pentosidine in the tissues of birds and determine factors that limit its accumulation
· Elucidating the antioxidant role of uric acid in health and disease

Recent Publications (since 1996):
· Klandorf, H., Zhou, Q., and Sams, A. (1996). Inhibition by aminoguanidine of glucose-derived collagen cross-linking in skeletal muscle of broiler breeder hens. Poult. Sci. 75:432-437.
· Klandorf, H., Boyce, C.S., Killefer, J., McGowan, J.A., Peterson, R.A., Valent, M., and Deaver, D.A. (1997). The effect of photoperiod and food intake on daily changes in plasma calcitonin in broiler breeder hens. Gen. Comp. Endocrinol. 107:327-340.
· Iqbal, M., Probert, L.L., and Klandorf, H. (1997). Effect of aminoguanidine on tissue pentosidine and production parameters in broiler breeder hens. Poult. Sci. 76:1574-1579.
· Kocamis, H., Kirkpatrick-Keller, D.C., Klandorf, H. and Killefer, J. (1998). In Ovo Administration of Recombinant Human Insulin-like growth factor-I (rh IGF-I) alters postnatal growth and development of the broiler chicken. Poult. Sci. 77:1913-1919.
· Iqbal, M., Probert, L.L., Al-humadi, N.H. and Klandorf, H. (1999). Protein glycosylation and advanced glycosylated endproducts (AGE) accumulation: an avian solution. J. Geront.: Biological Sciences 54A, B171-176.
· Klandorf, H., Boyce, C.S., Holt, S.B., Iqbal, M., Killefer, J., Peterson, R.A., and Deaver, D.R. (1999). Effect of thyroid hormone on concentrations of plasma calcitonin in broiler chicks. Comp. Biochem. Physiol. 122:55-60.
· Iqbal, M., Kenney, P.B., and Klandorf, H. (1999). Age-related changes in meat tenderness and tissue pentosidine: effect of diet restriction and aminoguanidine in broiler breeder hens. Poult. Sci. 78, 1328-1333.
· Klandorf, H., Probert, L.L., and Iqbal, M. (1999). In the defense against hyperglycemia: an avian strategy. World Poultry Science 55, 1-18.
· Iqbal, M., Al-Humadi, N.H., Kenney, P.B., Klandorf, H. (2000). Age-related changes in the mechanical properties and pentosidine in tendon: effect of diet restriction and aminoguanidine. Poult. Sci. 78, 1338-1344.
· Klandorf, H., Rathore, D.S., Iqbal, M., Shi, X., Simoyi, M., and Van Dyke, K. (2001). Acceleration of tissue aging in chickens caused by oxidative stress and detected by humoral chemiluminescence. pp 791-796 In: Luminescence Biotechnology: Instruments and Applications. Ed. K. Van Dyke. CRC Press.
· Simoyi, M.F., Van Dyke, K., and Klandorf, H. Manipulation of plasma uric concentration in broiler chicks and its effect on luminol-based chemiluminescence dependent oxidative stress. Am. J. Physiol. 282:R791-796.
· Lea, R.B. and Klandorf, H. (2002). The Brood Patch. In: Avian Eggs and Incubation. Ed. Charles Deeming. Oxford University Press.
· Chaney, R., Blemings, K.P., Bonner, J. and Klandorf, H. Pentosidine as a measurement of chronological age in wild birds. Auk (Accepted for publication).
· Simoyi, M.F. and Klandorf, H. (2003). Fructose and its Effect on Turkey Plasma Uric Acid Levels and Productive Performance. Poult. Sci. 82, 478-483.