Education

Eastern Michigan University, 1971, B.S.
University of South Carolina, 1976 Ph.D.
Medical University of South Carolina, 1981, M.D.

Research Interests

The pathophysiology of the urinary system. The role of stress response gene regulation in the development of interstitial cystitis. The role of the metallothionein gene family in mediating chemotherapeutic resistance to cisplatin in transitional cell carcinoma of the bladder.

Recent Publications

Todd JH, Sens DA, Hazen-Martin DJ, Sens MA: Aminoglycoside antibiotics alter the paracellular transport properties of cultured human proximal tubule cells. Toxicol Pathol. 22:56-67, 1994.

Smyth BJ, Todd JH, Bylander JE, Sens DA, Sens MA: Selective exposure of human proximal tubule cells to gentamicin provides evidence for a basolateral component of toxicity. Toxicol. Lett. 74:1-13, 1994.

Mididoddi S, McGuirt JP, Sens MA, Todd JH, Sens DA: Isoform-Specific expression of metallothionein mRNA in the developing and adult human kidney. Toxicol. Lett. 85:17-27, 1996.

Khan W, McGuirt JP, Sens MA, Sens DA, Todd JH: Expression of heat shock protein 27 in developing and adult human kidney. Toxicol. Lett. 84:69-79, 1996.

Hoey JG, Garrett SH, Sens MA, Todd JH, Sens DA: Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma. Toxicol. Lett. In Press.

Somji S, Garrett SH, Todd JH, Sens DA, Lamm DL, Sens MA: Metallothionein isoform gene expression in four human bladder cancer cell lines. J. Urol. Under Review, 1997.

Sens MA, Somji S, Todd JH, Garrett SH, Nseyo UO, Sens DA: Expression of heat shock protein 27 in human bladder. J. Urol. Under Review, 1997.